CHLOROGENIC ACID PERMEATION ACROSS INTESTINAL CELL MONOLAYERS: INFLUENCE BY CIRCADIAN RHYTHMS IN THE PRESENCE OF OTHER NATURAL POLYPHENOLS AND BY DOPAMINERGIC NEURONAL-LIKE CELLS

Poor oral bioavailability limits chlorogenic acid (CGA) benefits on the gut-brain axis.In Trucker Caps this study we demonstrate the existence of an active circadian-dependent efflux for the CGA intestinal permeation, leading to greater bioavailability in the evening rather than in the morning.As therapeutic/nutraceutical polyphenols can mutually i

Abstract Background Human Other respiratory syncytial virus (HRSV) is the most important virus causing lower respiratory infection in young children.The complete genetic characterization of RSV clinical strains is a prerequisite for understanding HRSV infection in the clinical context.Current information about the genetic structure of the HRSV geno

Modern threats to international peace and security from so called “Hybrid Threats”, multimodal threats such as cyber war, low intensity asymmetric conflict scenarios, global terrorism etc.which involve a diverse and broad community of affected stakeholders involving both regional and international organisations/structures, also pose further que